Bivalent opioid peptides synthesized from μ selective monomers display preferential selectivity for δ receptors

DOI: 10.1016/0223-5234(90)90161-U

Source and publish data:

European Journal of Medicinal Chemistry p. 29 - 33 (1990)

Update date:2022-08-05

Topics:

Authors:

Ronsisvalle, Giuseppe

Pappalardo, Maria S.

Pasquinucci, Lorella

Vittorio, Franco

Salvadori, Severo

et al. et al.

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Article abstract of DOI:10.1016/0223-5234(90)90161-U

A series of dimeric opioid peptides derived from μ selective compounds was synthesized to investigate whether μ and δ receptors coexist as distinct recognition sites on the same receptor complex.Some compounds were several times more potent than the corre

Full text of DOI:10.1016/0223-5234(90)90161-U

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