Angewandte Chemie - International Edition p. 14748 - 14752 (2015)
Update date:2022-08-02
Topics:
Simonin, Céline
Awale, Mahendra
Brand, Michael
Van Deursen, Ruud
Schwartz, Julian
Fine, Michael
Kovacs, Gergely
H?fliger, Pascal
Gyimesi, Gergely
Sithampari, Abilashan
Charles, Roch-Philippe
Hediger, Matthias A.
Reymond, Jean-Louis
Herein, we report the discovery of the first potent and selective inhibitor of TRPV6, a calcium channel overexpressed in breast and prostate cancer, and its use to test the effect of blocking TRPV6-mediated Ca2+-influx on cell growth. The inhib
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