Derivatives of a Novel Cyclopeptolide. 2. Synthesis, Activity against Multidrug Resistance in CHO and KB Cells in Vitro, and Structure-Activity Relationships

DOI: 10.1021/jm00039a003

Source and publish data:

Journal of Medicinal Chemistry p. 1918 - 1928 (1994)

Update date:2022-09-26

Topics:

Authors:

Emmer, Gerhard

Grassberger, Maximilian A.

Schulz, Gerhard

Boesch, Danielle

Gaveriaux, Claire

Loor, Francis

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00039a003

A series of derivatives of the novel cyclopeptolide 1 was prepared, and their ability to chemosensitize multi drug resistant CHO and KB cells in vitro was evaluated.In contrast to the parent compound, several of the derivatives were found to be highly act

Full text of DOI:10.1021/jm00039a003

Products guided by the article

Product name:cyclo-

Cas No:129816-70-2

R&D Labs maybe for 129816-70-2

xujianqiang

Contact:86-21-57725962

Address:shanghai
Shijiazhuang Haotian Chemical Co., Ltd.

Contact:86-311-85044374

Address:293 Donggang Road
Taizhou Huading Chemical Co.,Ltd(expird)

Contact:+86-576-88583898

Address:Economic&Technology development zone,Taizhou City,Zhejiang Province,China
Changzhou Hopschain Chemical Co.,Ltd

website:http://www.hopschem.cn/products.html

Contact:86-519-85528066

Address:Room 710, Unit A, Xingbei Development Mansion, Tongjiang Road, Changzhou City,213000, China
Jinan Trio PharmaTech Co., Ltd

Contact:86-531-88811783；+(0)13153010282

Address:2766 Yingxiu Road, Jinan High-Tech Zone, China

Relevant to this article

Electron-rich PNP-and PNN-type ruthenium(ii) hydrido borohydride pincer complexes. synthesis, structure, and catalytic dehydrogenation of alcohols and hydrogenation of esters

Doi:10.1021/om200595m
(2011)
Visible-light-driven metal-free aerobic synthesis of highly diastereoselective phosphinoylpyrroloindoles

Doi:10.1039/c9ob02730k
(2020)
THE CYCLOCONDENSATION REACTION OF 1-BENZOYLOXY-2-TERT-BUTYL-DIMETHYLSILYLOXY-4-METHOXY-1,3-BUTADIENE WITH N,O-PROTECTED D-THREONINALS AND D-ALLO-THREONINALS

Doi:10.1016/S0040-4020(01)80942-X
(1991)
Multiple organolithium generation in the continuous flow synthesis of amitriptyline

Doi:10.1002/adsc.201300614
(2013)
Absorption tuning of monosubstituted triazatruxenes for bulk heterojunction solar cells

Doi:10.1021/ol202443g
(2011)
Extended targeting potential and improved synthesis of Microcin C analogs as antibacterials

Doi:10.1016/j.bmc.2011.07.052
(2011)

Article Doi