Directed regiochemical control in the ring expansion reactions of a substituted trans-decalone

Article abstract of DOI:10.1016/S0040-4039(00)88999-6

A derivative of the Wieland-Miescher ketone can selectively be converted into either regioisomeric ring-expanded lactam. The synthesis of the diastereomeric N-α-methylbenzyl oxaziridine derivatives determines the regiochemistry of the product lactam and a