Chemical and Pharmaceutical Bulletin p. 287 - 291 (1993)
Update date:2022-08-02
Topics:
Kawate
Nakagawa
Yamazaki
Hirayama
Hino
A new general procedure for the alkylation of the C = N double bond of 3,4-dihydro-β-carboline has been developed with amphiphilic reaction systems such as BF3 · OEt2/RLi, RMgX, R2CuLi or trimethylsilyl trifluoromethanesulfonate/RLi, RMgX to give the corresponding 1-substituted-1,2,3,4-tetrahydro-β-carbolines.
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