Synthesis and Antiarrhythmic Activity of 5,11-Dihydrobenzoxepinopyridines

DOI: 10.1021/jm00173a029

Source and publish data:

Journal of Medicinal Chemistry p. 3095 - 3100 (1990)

Update date:2022-07-31

Topics:

Authors:

Kumazawa, Toshiaki

Harakawa, Hiroyuki

Obase, Hiroyuki

Oiji, Yoshimasa

Nito, Masaaki

et al. et al.

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Article abstract of DOI:10.1021/jm00173a029

During further modification of the new antiulcer agent 5 (KW-5805), a 5,11-dihydro<1>benzoxepino<3,4-b>pyridine derivative, we found that some new derivatives had antiarrhythmic activity.So we continued synthesis and evaluation of a series of 5-substitute

Full text of DOI:10.1021/jm00173a029

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Product name:N,N-Diethyl-N'-(7-methoxy-5,11-dihydro-10-oxa-1-aza-dibenzo[a,d]cyclohepten-5-yl)-ethane-1,2-diamine

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