A NEW AND NOVEL APPROACH TOWARDS THE SYNTHESIS OF 3'-DEOXY-3'-HYDROXYMETHYL RIBOFURANOSIDES

Article abstract of DOI:10.1016/S0040-4039(00)94705-1

The synthesis of 1,2,5-tri-O-benzoyl-3-deoxy-3-<(benzyloxy)methyl>-α,β-D-ribofuranose (1) from 1,2-O-isopropylidene-α-D-xylofuranose (2) has been achieved in an overall yield of 37percent.Compound 1 is a properly substituted intermediate for the synthesis