Tetrahedron Letters p. 4227 - 4228 (1990)
Update date:2022-07-30
Topics:
Fell, Stephen C. M.
Harbridge, John B.
Ozonolysis, followed by a reductive work up of 2,5-dimethoxy-2,5-dihydrofuran generates the symmetrical bis-aldehyde (9) which reacts in situ with certain stabilized phosphoranes. Hydrolysis of the resultant alkene acetals affords 4-hydroxybutenolides (1) end (2).
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