Tetrahedron Letters p. 7171 - 7174 (1993)
Update date:2022-08-05
Topics:
Shankar, B. B.
Kirkup, M. P.
McCombie, S. W.
Ganguly, A. K.
A variety of 2,6-substituted trihydroxy piperidines 4 was synthesized with stereocontrol from the corresponding 2,6 bis-(Benzotriazolyl) trihydroxy piperidine 9, which in turn was prepared from 1,2-O-isopropylidene-D-glucofuranose 5 employing a simple, two step chemical manipulation.These products are potential glycosidase inhibitors and can be transformed to other useful chiral products.
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