Alkaline hydrolysis of some erythronolide a derivatives

DOI: 10.1016/S0040-4039(00)97445-8

Source and publish data:

Tetrahedron Letters p. 3687 - 3690 (1990)

Update date:2022-08-03

Topics:

Authors:

Sakan Sakan

Babirad Babirad

Smith Smith

Houk Houk

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)97445-8

The saponification of certain protected benzylidene C.3-C.5, C.9-C.11 erythronolide-A derivatives is described. A remarkable solvent effect was noted which eliminates the formation of side-products during the alkaline hydrolysis.

Full text of DOI:10.1016/S0040-4039(00)97445-8

Products guided by the article

Product name:(R)-2-((4S,6R)-6-{(1R,3R)-3-[(4S,5S,6R)-6-((2R,3S)-3-Ethyl-2-methyl-oxiranyl)-5-methyl-2-phenyl-[1,3]dioxan-4-yl]-1-hydroxy-1-methyl-butyl}-5-methyl-2-phenyl-[1,3]dioxan-4-yl)-propionic acid

Cas No:130532-36-4

R&D Labs maybe for 130532-36-4

BOC Sciences

website:https://www.bocsci.com/

Contact:1-631-485-4226

Address:Ramsey Road
Water Chemical Co.,LTD

Contact:+86-21-6856-1349 523-87676172

Address:No16 . BinJiang Road . Taixing Economy Developing Area .JiangSu Province . China
Tianjin Boron PharmaTech Co.,Ltd.(expird)

Contact:86-022-59845187

Address:B9-401, Tianda Science Park,No.80,4th Avenue,TEDA,Tianjin, China
Yancheng Smiling Imp & Exp Co., Ltd.

Contact:+86-515-83173586

Address:Rm1207, BLD#03, Phoenix Plaza, Juheng Road, Yancheng, Jiangsu, P.R. China
Shanghai Yudiao Chemistry Technology Co.,Ltd

Contact:0086-18964703211

Address:Building NO.5, NO.218,Rongtian Road,ganxiang town,Jinshan District,shanghai,201518,china

Relevant to this article

Mechanistic Studies on Dopamine β-Monooxygenase Catalysis: N-Dealkylation and Mechanism-Based Inhibition by Benzylic-Nitrogen-Containing Compounds. Evidence for a Single-Electron-Transfer Mechanism

Doi:10.1021/ja00247a033
(1987)
Hydrogen and amine activation by a frustrated Lewis pair of a bulky N-heterocyclic carbene and B(C₆F₅)₃

Doi:10.1002/anie.200802596
(2008)
Oxygen-sensing properties of 5, 10, 15, 20-tetraphenylporphinato platinum(II) and palladium(II) covalently bound on poly(isobutyl-co-2,2,2-trifluoroethyl methacrylate)

Doi:10.1002/pola.23818
(2010)
Chemical synthesis of 3-amino-2,3-dideoxy-D-inositol (an intermediate in the biosynthesis of 2-deoxystreptamine) and its D-epi stereoisomers

Doi:10.1016/S0008-6215(00)90119-8
(1986)
Synthesis of 3,5-disubstituted-1,2,4-oxadiazoles using tetrabutylammonium fluoride as a mild and efficient catalyst

Doi:10.1016/S0040-4039(00)02288-7
(2001)
Preparation of imidazolidin-4-ones and their evaluation as hydrolytically cleavable precursors for the slow release of bioactive volatile carbonyl derivatives

Doi:10.1002/ejoc.201200081
(2012)

Article Doi