Synthesis of Leu-Abu(P) and Glu-Abu( P)-Leu. Isosteres of ser(P)-peptides

DOI: 10.1016/S0040-4039(00)97464-1

Source and publish data:

Tetrahedron Letters p. 3759 - 3762 (1990)

Update date:2022-08-04

Topics:

Authors:

Tong Tong

Perich Perich

Johns Johns

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Article abstract of DOI:10.1016/S0040-4039(00)97464-1

Boc-Asp-O₁-Bu was efficiently converted to Boc-Abu(PO₃Me₂)-O₁-Bu in five steps then to Boc-Abu(PO₃Me₂)OH in two steps. Both the protected amino acids were used in the syntheses of Boc-Leu-A

Full text of DOI:10.1016/S0040-4039(00)97464-1

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