MICROBIAL OXIDATION IN SYNTHESIS: PREPARATION OF 6-DEOXY CYCLITOL ANALOGUES OF MYO-INOSITOL 1,4,5-TRIPHOSPHATE FROM BENZENE

DOI: 10.1016/S0040-4039(00)99439-5

Source and publish data:

Tetrahedron Letters p. 3557 - 3560 (1989)

Update date:2022-09-26

Topics:

Authors:

Ley, Steven V.

Parra, Margarita

Redgrave, Alison J.

Sternfeld, Francine

Vidal, Angel

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Article abstract of DOI:10.1016/S0040-4039(00)99439-5

The novel 6-deoxy, 6-deoxy-6-fluoro and 6-deoxy-6-methyl myo-inositol 1,4,5-triphosphate derivatives (4), (5) and (6) were derived from benzene via microbial oxidation to cis -1,2-dihydroxycyclohexa-3,5-diene (2) and conversion through to the key epoxyace

Full text of DOI:10.1016/S0040-4039(00)99439-5

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