STUDIES ON TUMOR PROMOTERS. 10. SYNTHESIS OF THE ABC RING SYSTEM OF THE TIGLIANES AND DAPHNANES BY A ZIRCONIUM-MEDIATED INTRAMOLECULAR ENYNE CARBOCYCLIZATION

Article abstract of DOI:10.1016/S0040-4039(00)97446-X

A novel synthetic route to the ABC ring system of the daphnanes and tiglianes based on intramolecular enyne carbocyclization is described that provides access to a new family of diterpene tumor promotor analogs.