
Tetrahedron Letters p. 4949 - 4952 (1990)
Update date:2022-08-04
Topics:
Bernardi
Micheli
Potenza
Scolastico
Villa
Statin analogues can be synthesized stereoselectively (diastereomeric ratios up to 4:1) starting from malic acid. The key step involves an unprecedented cis-selective allylation of an α-alkoxy N-acyliminium ion.
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