A general route to "carba" peptide bond replacements: Unequivocal synthesis of Boc-L-Phe-ψ(CH2-CH2)-L-Ala-OH and Boc-L-Phe-ψ(CH2-CH2)-D-Ala-OH

DOI: 10.1016/S0040-4039(00)97829-8

Source and publish data:

Tetrahedron Letters p. 5153 - 5156 (1990)

Update date:2022-08-02

Topics:

Authors:

Rodriguez, Marc

Aumelas, Andre

Martinez, Jean

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Article abstract of DOI:10.1016/S0040-4039(00)97829-8

An unambiguous synthesis of Boc-_L-Phe-ψ(CH₂-CH₂)-_L-Ala-OH and Boc_L-Pheψ(CH₂-CH₂)-_D-AlaOH from Boc-_L-phenylalanine, through lactame intermediates (3R,6R)-3-m

Full text of DOI:10.1016/S0040-4039(00)97829-8

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Product name:(E)-(R)-5-tert-Butoxycarbonylamino-2-methyl-6-phenyl-hex-2-enoic acid methyl ester

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