A novel synthesis of 3-halo-2-phenylquinoline-4-carboxylic acids

Article abstract of DOI:10.1002/jhet.5570340235

The 3-chloro and 3-bromo-2-phenylquinoline-4-carboxylic acids were obtained in good yields through a novel procedure, entailing the synthesis of the 3-amino intermediate and the subsequent replacement of the amino group with chlorine or bromine, according to the Sandmeyer reaction.