Amino acids as suitable N-nucleophiles for the aza-Michael reaction of vinylphosphoryl compounds in water

DOI: 10.1016/j.tetlet.2011.09.111

Source and publish data:

Tetrahedron Letters p. 6562 - 6565 (2011)

Update date:2022-08-05

Topics:

Authors:

Matveeva, Ekaterina V.

Shipov, Anatoly E.

Petrovskii, Pavel V.

Odinets, Irina L.

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Article abstract of DOI:10.1016/j.tetlet.2011.09.111

Application of water as a sole solvent promotes the aza-Michael reaction of diethyl vinylphosphonate and diphenylvinylphosphine oxide with α-substituted amino acid sodium salts generated in situ to afford the corresponding β-aminophosphonates and β-aminop

Full text of DOI:10.1016/j.tetlet.2011.09.111

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