Novel β-carboline-tripeptide conjugates attenuate mesenteric ischemia/reperfusion injury in the rat

DOI: 10.1016/j.ejmech.2011.03.029

Source and publish data:

European Journal of Medicinal Chemistry p. 2441 - 2452 (2011)

Update date:2022-08-05

Topics: Apoptosis Antioxidant in vivo Oxidative Stress Statistical Significance Conjugate Animal model Free radicals Tripeptide β-carboline Western blot TUNEL assay ELISA (Enzyme-Linked Immunosorbent Assay) Necrosis

Authors:

Bi, Wei Bi, Wei

Bi, Yue Bi, Yue

Xue, Ping

Zhang, Yanrong

Gao, Xiang

Wang, Zhibo

Li, Meng

Baudy-Floc'H, Michele

Ngerebara, Nathaniel

Li, Xiaoxu

Gibson, K. Michael

Bi, Lanrong

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Article abstract of DOI:10.1016/j.ejmech.2011.03.029

We have synthesized a series of new β-carboline-tripeptide conjugates, and examined their anti-inflammatory properties in a mouse model of xylene-induced ear edema. The analgesic capacity of these compounds was further evaluated in a rodent tail flick ass

Full text of DOI:10.1016/j.ejmech.2011.03.029

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