A general copper-BINAP-catalyzed asymmetric propargylation of ketones with propargyl boronates

DOI: 10.1021/ja2028958

Source and publish data:

Journal of the American Chemical Society p. 10332 - 10335 (2011)

Update date:2022-07-29

Topics:

Authors:

Fandrick, Keith R.

Fandrick, Daniel R.

Reeves, Jonathan T.

Gao, Joe

Ma, Shengli

Li, Wenjie

Lee, Heewon

Grinberg, Nelu

Lu, Bruce

Senanayake, Chris H.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/ja2028958

An operationally simple copper-BINAP-catalyzed, highly enantioselective propargylation of ketones is presented. The methodology was developed as an enantioselective process for methyl ethyl ketone and shown to be applicable to a wide variety of prochiral

Full text of DOI:10.1021/ja2028958

Products guided by the article

Product name:(R)-2-(1-tosyl-1H-indol-3-yl)-5-(trimethylsilyl)pent-4-yn-2-ol

Cas No:1312791-23-3

R&D Labs maybe for 1312791-23-3

SHANDONG ZHANHUA YONGHAO PHARMACEUTICAL TECH.CO.,LTD

Contact:+86-576-88685096

Address:GENGJU VILLAGE NORTH ONE KILOMETER,ZHANHUA DISTRICT,BINZHOU CITY,SHANDONG PROVINCE,CHINA.
EnBridge PharmTech Co., Ltd.

website:http://www.enbridgepharm.com

Contact:+86-510-83591909

Address:Huishan Zone, Wuxi City, Jiangsu Province, P.R.China
Hangzhou Taiyan Trading Co., Ltd(expird)

Contact:+86-13777583958

Address:NO.63, Xingyi Street, Xihu District, Hangzhou, Zhejiang, China
Weihao Chemtech (ChangZhou) Co., Ltd.(expird)

Contact:051989185693

Address:NO 217 huangshan Rd ,Changzhou
Shao Xing Empire Import&Export CO.,ltd

Contact:86-575-82127757

Address:11#, Weiwu Road, Shangyu Industrial Park, Hangzhou Bay, Hangzhou, Zhejiang Province, China

Relevant to this article

Synthesis of C8-N9 annulated purines by iron-catalyzed C-H amination

Doi:10.1002/chem.201301248
(2013)
Synthesis and reactivity of 6H-dibenzo[c,e][1,2]oxaphosphinine 6-sulfide, a novel thiophosphacyclic molecule

Doi:10.3987/COM-10-12124
(2011)
The first generation of β-galactosidase-responsive prodrugs designed for the selective treatment of solid tumors in prodrug monotherapy

Doi:10.1002/anie.201204935
(2012)
Synthesis of acyclic nucleoside analogs of 6-substituted 2-aminopurines and 2-amino-8-azapurines

Doi:10.1002/jhet.5570270542
(1990)
Perylene anhydride fused porphyrins as near-infrared sensitizers for dye-sensitized solar cells

Doi:10.1021/ol201303h
(2011)
Pd-catalyzed asymmetric hydrogenation of C=C bond of α,β- unsaturated ketones

Doi:10.1055/s-0030-1259725
(2011)

Article Doi