Diastereoselectivity in the Addition of Grignard Reagents to Ketones Controlled by the 1,3-Dithiane 1-Oxide Asymmetric Building Block

DOI: 10.1016/S0040-4020(01)80562-7

Source and publish data:

Tetrahedron p. 10355 - 10368 (1993)

Update date:2022-07-29

Topics:

Authors:

Page, Philip C. Bulman

Prodger, Jeremy C.

Westwood, Donald

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Article abstract of DOI:10.1016/S0040-4020(01)80562-7

2-Acyl-1,3-dithiane 1-oxide undergo diastereoselective addition of Grignard reagents; the degree of selectivity observed is highly dependent upon the solvent and the halide counter-ion used; very high selectivities have been observed under certain reactio

Full text of DOI:10.1016/S0040-4020(01)80562-7

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