Alcynylsilanes functionnels I. Synthese regiospecifique par voie organozincique d'alcools homopropargyliques trialkylsilyles α'- ou ω'-chlores

Article abstract of DOI:10.1016/0022-328X(90)80230-W

In many cases, the reaction between α- or ω-chloro carbonyl derivatives and organozincs prepared from halides R3Si-C<*>C-CH2Br is chemo- and regioselective: it affords, in a good yield, trialkylsilyl homopropargylic alcohols α'- or ω'-substituted by a chlorine atom.This behaviour is different of this of organoaluminiums which lead mainly to trialkylsilyl α-allenyl α'- or ω'-chlorinated alcohols.