New nitric oxide or hydrogen sulfide releasing aspirins

DOI: 10.1021/jm2004514

Source and publish data:

Journal of Medicinal Chemistry p. 5478 - 5484 (2011)

Update date:2022-07-29

Topics:

Authors:

Lazzarato, Loretta

Chegaev, Konstantin

Marini, Elisabetta

Rolando, Barbara

Borretto, Emily

Guglielmo, Stefano

Joseph, Sony

Di Stilo, Antonella

Fruttero, Roberta

Gasco, Alberto

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Article abstract of DOI:10.1021/jm2004514

A new series of (((R-oxy)carbonyl)oxy)methyl esters of aspirin (ASA), bearing nitric oxide (NO) or hydrogen sulfide (H₂S) releasing groups, was synthesized, and the compounds were evaluated as new ASA co-drugs. All the products were quite stabl

Full text of DOI:10.1021/jm2004514

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