
Journal of Medicinal Chemistry p. 1011 - 1018 (1991)
Update date:2022-07-30
Topics:
Mylari
Beyer
Siegel
Ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate (1, EBPC) is a potent and specific inhibitor of aldose reductase. It was >4000X more potent in its inhibition of rat lens aldose reductase than the closely related rat or pig kidney aldehyde reductas
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