Gem-Difluoroallylation of Aldehydes and Ketones as a Convenient Route to α,α-Difluorohomoallylic Alcohols

DOI: 10.1021/jo00003a025

Source and publish data:

Journal of Organic Chemistry p. 1037 - 1041 (1991)

Update date:2022-08-02

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Authors:

Yang, Zhen-Yu

Burton, Donald J.

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Article abstract of DOI:10.1021/jo00003a025

In the presence of zinc, 3-bromo-3,3-difluoropropene or 3-iodo-1,1-difluoropropene reacted with carbonyl compounds to give the corresponding α,α-difluorohomoallylic alcohols in good yields at 0 deg C to room temperature.The reaction is applicable to aliph

Full text of DOI:10.1021/jo00003a025

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