Synthesis of the C12-C26 fragment of the acyltetronic acid ionophore antibiotic tetronasin (ici 139603)

DOI: 10.1016/S0040-4039(00)97889-4

Source and publish data:

Tetrahedron Letters p. 5525 - 5528 (1990)

Update date:2022-07-29

Topics:

Authors:

De Laszlo, Stephen E.

Ford, Mark J.

Ley, Steven V.

Maw, Graham N.

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Article abstract of DOI:10.1016/S0040-4039(00)97889-4

Preparation of a central tetrahydropyran portion (2) of the antibiotic tetronasin (1) was achieved using an all-in-one epoxidation / cyclization modification of the Sharpless reaction. Further manipulation and coupling reactions afforded the C12-C26 fragm

Full text of DOI:10.1016/S0040-4039(00)97889-4

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