Synthesis and biological activity of new halo-steroidal antiestrogens

DOI: 10.1021/jm00109a014

Source and publish data:

Journal of Medicinal Chemistry p. 1624 - 1630 (1991)

Update date:2022-07-29

Topics:

Authors:

Levesque

Merand Merand

Dufour Dufour

Labrie Labrie

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00109a014

Antiestrogen therapy is the most widely used endocrine manipulation for the treatment of breast cancer, especially in postmenopausal women. Unfortunately, the compounds presently available possess mixed agonistic/antagonistic activity, thus potentially li

Full text of DOI:10.1021/jm00109a014

Products guided by the article

Product name:Estra-1,3,5(10)-triene-7-undecanamide,Nbutyl- 16-chloro-3,17-dihydroxy-N-methyl-,(7R,16R,17R)-

Cas No:131811-55-7

R&D Labs maybe for 131811-55-7

HANGZHOU PANYU CHEMICAL CO.,LIMITED

Contact:+86-571-86578491

Address:Rm 605, NO.1870 Binsheng Road,Binjiang Dist, Hangzhou, China
Taizhou Huading Chemical Co.,Ltd(expird)

Contact:+86-576-88583898

Address:Economic&Technology development zone,Taizhou City,Zhejiang Province,China
Shanggao Ruiya Fine Chemicals Co., Ltd

Contact:+86-795-2592103

Address:Xingguang Nanlu,Shanggao County Industry Park
Advanced Biotech

Contact:+1-973-357-0577

Address:10 Taft Rd.
wuxi leji biology technology co., LTD

website:http://www.lejibio.com/

Contact:18362718864

Address:The Nanyue Road No. 2, Yixing City, Jiangsu Province

Relevant to this article

Unidirectional redox-stimulated movement around a C-C single bond

Doi:10.1002/chem.201003682
(2011)
Efficient Br?nsted acid catalyzed hydrations and hydroaminations of (dicyclopropylmethylene)cyclopropane

Doi:10.1055/s-0030-1260769
(2011)
Toward the total synthesis of bryostatin 11: Stereoselective construction of the C13-exocyclic enoate in the C1-C16 fragment

Doi:10.1080/00397911.2010.516462
(2011)
Indium(III)-Catalyzed Cyclization of Aromatic 5-Enynamides: Facile Synthesis of 2-Aminonaphthalenes, 2-Amino-1H-indenes, and 2,3-Dihydro-1H-indeno[2,1-b]pyridines

Doi:10.1002/adsc.201500449
(2015)
DIASTEREOCONTROL IN RHODIUM-CATALYZED HYDROBORATION OF CHIRAL ACYCLIC ALLYLIC ALCOHOL DERIVATIVES

Doi:10.1016/S0040-4039(00)95210-9
(1989)
Absolute Configuration of Hydroazulenoid Diterpenes Based on Circular Dichroism

Doi:10.1021/jo00008a018
(1991)

Article Doi