Synthesis and biological activity of new halo-steroidal antiestrogens

DOI: 10.1021/jm00109a014

Source and publish data:

Journal of Medicinal Chemistry p. 1624 - 1630 (1991)

Update date:2022-07-29

Topics:

Authors:

Levesque

Merand Merand

Dufour Dufour

Labrie Labrie

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Article abstract of DOI:10.1021/jm00109a014

Antiestrogen therapy is the most widely used endocrine manipulation for the treatment of breast cancer, especially in postmenopausal women. Unfortunately, the compounds presently available possess mixed agonistic/antagonistic activity, thus potentially li

Full text of DOI:10.1021/jm00109a014

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