Acetic anhydride generated imidazolium ylide in ring closures onto carboxylic acids; Part of the synthesis of new potential bioreductive antitumor agents

DOI: 10.1055/s-0030-1260543

Source and publish data:

Synlett p. 1097 - 1100 (2011)

Update date:2022-08-03

Topics:

Authors:

Joyce, Eamonn

McArdle, Patrick

Aldabbagh, Fawaz

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Article abstract of DOI:10.1055/s-0030-1260543

Acetic anhydride behaves as a traceless activating agent allowing thermal intramolecular condensation of 2-(benzimidazol-1-ylmethyl) benzoic and nicotinic acids. Autoxidation gives benzimidazo[1,2-b]isoquinoline-6,11-diones (intermediates characterized) a

Full text of DOI:10.1055/s-0030-1260543

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Product name:2-[(4,7-dimethoxy-1H-benzimidazol-1-yl)methyl]benzoic acid

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