SYNTHESIS OF 11,12,12a,13-TETRAHYDRO-6H-INDOLOBENZODIAZEPINES

DOI: 10.1007/BF00756424

Source and publish data:

Chemistry of Heterocyclic Compounds p. 681 - 682 (1990)

Update date:2022-08-03

Topics:

Authors:

Shachkus, A. A.

Degutis, Yu. A.

Myadyakshene, G. S.

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Article abstract of DOI:10.1007/BF00756424

Alkylation of 2,3,3-trimethyl- and 2,3,3,5-tetramethyl-3H-indoles with 2-bromomethylbenzonitrile gave 2-methylene-1-(2-cyanobenzyl)-2,3-dihydro-1H-indoles.When reacted with lithium aluminum hydride the latter are cyclized to 11,12,12a,13-tetrahydro-6H-indolo<1,2-b><2,4>benzodiazepines.

Full text of DOI:10.1007/BF00756424

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