SELECTIVE ACID HYDROLYSIS OF 2-SUBSTITUTED-5-DIMETHYLAMINOMETHYLENEAMINOPYRIMIDINES TO 5-AMINO- AND 5-HYDROXYPYRIMIDINES

DOI: 10.1007/BF00756420

Source and publish data:

Chemistry of Heterocyclic Compounds p. 668 - 670 (1990)

Update date:2022-08-05

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Authors:

Kizner, T. A.

Mikhaleva, M. A.

Serebryakova, E. S.

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Article abstract of DOI:10.1007/BF00756420

Conditions are described for the selective acid hydrolysis of 2-substituted-5-dimethylaminomethyleneaminopyrimidines in 0.2-2 M sulfuric acid, to give high yields of the corresponding 5-amino- and difficultly accessible 5-hydroxypyrimidines.

Full text of DOI:10.1007/BF00756420

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