Synthesis of 1-(3-R-amino-4-hydroxy butyl)thymine acyclonucleoside. Analogs as potential anti-AIDS drugs

DOI: 10.1016/S0040-4039(00)97758-X

Source and publish data:

Tetrahedron Letters p. 4879 - 4882 (1990)

Update date:2022-07-29

Topics:

Authors:

Genevois-Borella

Florent Florent

Monneret

Grierson

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Article abstract of DOI:10.1016/S0040-4039(00)97758-X

The 1-(3-R-amino-4-hydroxybutyl)thymine acyclonucleoside analogs 8-12,14, 16, 19, and the corresponding 3-aminomethyl derivatives 24-26 were prepared from the di-n-butyl ester of R-(-)-aspartic acid.

Full text of DOI:10.1016/S0040-4039(00)97758-X

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