Assignment of Stereochemistry in the Oligomycin/Rutamycin/Cytovaricin Family of Antibiotics. Asymmetric Synthesis of the Rutamycin Spiroketal Synthon

DOI: 10.1021/jo00313a011

Source and publish data:

Journal of Organic Chemistry p. 6260 - 6268 (1990)

Update date:2022-08-03

Topics:

Authors:

Evans, David A.

Rieger, Dale L.

Jones, Todd K.

Kaldor, Stephen W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00313a011

The absolute stereochemistry of the rutamycin antibiotics 2a,b has been established through asymmetric synthesis of the known degradation product 4.One of the key steps in the assemblage process involves acylation of the metalated hydrazone 6 with the N-m

Full text of DOI:10.1021/jo00313a011

Products guided by the article

Product name:(2S,3R,6R,8S,9S)-3,9-dimethyl-8-<(R)-2-hydroxy-1-propyl>-2-<(R)-3-<<(4-methoxyphenyl)methoxy>methyl>-1-pentyl>-1,7-dioxaspiro<5.5>undecan-4-one

Cas No:131685-64-8

R&D Labs maybe for 131685-64-8

Zhejiang Kaili Industrial Co., Ltd

Contact:+86-571-85241926

Address:lantian business center,No.18 Moganshan Road
WENZHOU M&C FOREIGN TRADE CO.,LTD.

Contact:+86-577-88862917

Address:No.8 Liming West Road,Wenzhou,zhejiang,China
PINGYUAN SIHUAN PHARMACEUTICAL CO., LTD

Contact:+86-531-55696072

Address:#2766,yinxiu Road, Economic Development Zone, Pingyuan Country, Shandong Province, China.
shijiazhuang shuanglian chemical industry co.,ltd

Contact:0311-82190302

Address:Luquan Intersection , Shijiazhuang--Taiyuan Expressway，Shijiazhuang City
Dalian Synco Chemical Co., Ltd.

Contact:+86-411-83635150

Address:Rm 1004, 24, Tangshan Street, Dalian

Relevant to this article

Highly stereoselective synthesis of α-hydroxy β-amino acids through β-lactams: Application to the synthesis of the taxol and bestatin side chains and related systems

Doi:10.1016/S0040-4039(00)97083-7
(1990)
Oligophenylenaminones as scaffolds for α-helix mimicry

Doi:10.1021/jo200917d
(2011)
Doi:10.1039/CT9089302077
(1908)
Synthesis of variously coupled conjugates of d-glucose, 1,3,4-oxadiazole, and 1,2,3-triazole for inhibition of glycogen phosphorylase

Doi:10.1016/j.carres.2011.03.004
(2011)
The First Nonconjugated Mononuclear Benzene Dianion. Isolation and Characterization of Bis<(tetrahydrofuran)lithium(I)> Hexakis(trimethylsilyl)benzenide

Doi:10.1021/ja00004a086
(1991)
Additional Nucleotide Derivatives of Mitosenes. Synthesis and Activity against Parental and Multidrug Resistant L1210 Leukemia

Doi:10.1021/jm00111a004
(1991)

Article Doi