
Journal of Organic Chemistry p. 1355 - 1357 (1991)
Update date:2022-08-02
Topics: Asymmetric synthesis Enantiomerically pure Chirality β-aryl-β-amino acids
Konopelski, Joseph P.
Chu, Kent S.
Negrete, George R.
Enantiomerically pure dihydropyrimidinone 1 reacts with aryl iodides in the presence of catalytic amounts of Pd(OAc)2 and added phosphine to afford dihydropyrimidinone 4, in which a formal conjugate addition of the aryl group to the α,β-unsaturated system
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