Four-component Condensation (Ugi Reaction) at High Pressure: Novel Synthesis of Peptides containing Very Bulky α,α-Disubstituted Glycines

Article abstract of DOI:10.1039/c39900001640

Peptides, Z-Val-X-Gly-OMe, containing a very bulky α,α-disubstituted glycine, such as N-benzyl-α,α-diisopropylglycine or N-benzyl-α,α-diphenylglycine, as the residue X can be synthesized in moderate yields by four-component condensation (Ugi reaction) at

Full text of DOI:10.1039/c39900001640

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