Synthetic Applications of Protected 2-Aryl-4-piperidones. 7. Synthesis of 1-Etylindoloquinolizidin-2-one

DOI: 10.1021/jo00022a015

Source and publish data:

Journal of Organic Chemistry p. 6292 - 6298 (1991)

Update date:2022-08-03

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Authors:

Rubiralta, Mario

Diez, Anna

Vila, Cristina

Troin, Yves

Feliz, Miguel

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Article abstract of DOI:10.1021/jo00022a015

The synthesis of 1-ethylindolo<2,3-a>quinolizidin-2-one (1) by the intramolecular cyclization of protected N-(2-hydroxyethyl)-2-<1-(phenylsulfonyl)-3-indolyl>-4-piperidone 15 by the action of K^tBuO and further acid treatment is reported.The met

Full text of DOI:10.1021/jo00022a015

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