Synthesis p. 917 - 920 (1990)
Update date:2022-08-03
Topics:
Nudelman, Norma S.
Lewkowicz, Elizabeth S.
Perez, Daniel G.
N,N,N',N'-tetrasubstituted ureas have been obtained in good yields by reaction of lithium aliphatic amides in tetrahydrofuran solution with carbon monoxide under mild conditions (0 deg C, 1013 mbar) followed by treatment with oxygen prior to work up.N,N,N',N'-tetrasubstituted oxomalonamides (oxopropanediamides) can be obtained under similar reaction conditions by carrying out the reaction in the presence of known amounts of the pure amine.Besides being an useful synthetic method, the present studies afford new evidence of the mechanism of the reaction.
View MoreShanghai Kefu Chemical Co.,Ltd.
Contact:+86-21-34616196
Address:Room601-602, Xuhui Business Building, No.168, Yude Road, Shanghai
Hangzhou Think Chemical Co. Ltd
website:http://www.thinkchem.com/
Contact:86-571-89986307/81956191/81956084/81956192
Address:Room 501-502, Tower E, Yuanjian Building, Yuanyang International Center, Hangzhou-310011, China
Suzhou Chiral Pharmaceuticals Co., Ltd.
Contact:86-0512-63197058
Address:Building A, No. 2358, Chang'an Road, Wujiang Science Park
Xinjiang Zhongtai Chemical Co., Ltd.
Contact:+86-991-8788172
Address:NO.78 XISHAN RD.URUMQI,CHINA
Jinan Hongfangde Pharmatech Co.,Ltd
Contact:86-531-88870908
Address:F Bldg. West Unit North Area of Univ. Tech. Garden Xinyu Rd. Jinan New & High Tech Industry Development Zone Shandong, China
Doi:10.1016/S0040-4020(01)00978-4
(2001)Doi:10.1016/S0957-4166(99)00484-X
(2000)Doi:10.1002/chem.200701679
(2008)Doi:10.1021/acs.inorgchem.9b02093
(2019)Doi:10.1021/ol017298y
(2002)Doi:10.1016/j.ejmech.2006.12.007
(2007)