Diastereoselective Addition of a Silylketene Acetal to Chiral α-Thioaldehydes

Article abstract of DOI:10.1016/S0040-4039(00)97160-0

Chiral α-thioaldehydes 2-6 undergo chelation or non-chelation controlled addition of silylketene acetal 1, depending on the nature of the Lewis acid catalyst and of the ligands at the stereocenter.