Synthesis and evaluation of oligodeoxynucleotides containing 3'-O-ethyl- 4'-C-(hydroxymethyl)thymidine: Introduction of a novel class of phosphodiester internucleoside linkages

Article abstract of DOI:10.1080/15257779408010674

3'-O-Ethyl-4'-C-(hydroxymethyl)thymidine (5) was synthesized and converted into the phosphoramidite building block 8. Novel oligodeoxynucleotide analogues containing 4'-C-hydroxymethyl phosphodiester internucleoside linkages were synthesized on an automat

Full text of DOI:10.1080/15257779408010674

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Nucleosides and Nucleotides
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Synthesis and Evaluation of
Oligodeoxynucleotides Containing 3′-O-
Ethyl-4′-C-(hydroxymethyl)thymidine:
Introduction of a Novel Class of
Phosphodiester Internucleoside Linkages
Lars H. Dreio⊘e a & Jesper Wengel a
a Department of Chemistr , dense University , DK-5230, Odense M,
Denmark
Published online: 24 Sep 2006.
To cite this article: Lars H. Dreio⊘e & Jesper Wengel (1994) Synthesis and Evaluation of
Oligodeoxynucleotides Containing 3′-O-Ethyl-4′-C-(hydroxymethyl)thymidine: Introduction of a Novel
Class of Phosphodiester Internucleoside Linkages, Nucleosides and Nucleotides, 13:9, 1939-1952, DOI:
10.1080/15257779408010674
To link to this article: http://dx.doi.org/10.1080/15257779408010674
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