A NEW SYNTHESIS OF 2',3'-DIDEOXYNUCLEOSIDES FOR AIDS CHEMOTHERAPY

DOI: 10.1016/S0040-4039(00)80265-8

Source and publish data:

Tetrahedron Letters p. 1239 - 1242 (1988)

Update date:2022-08-04

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Authors:

Farina, Vittorio

Benigni, Daniel A.

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Article abstract of DOI:10.1016/S0040-4039(00)80265-8

Dideoxynucleosides were prepared in high optical purity from L-glutamic acid.The condensation reactions between activated 2,3-dideoxypentofuranoses and silylated purines or pyrimidines afforded separable β/α mixtures of dideoxynucleosides.

Full text of DOI:10.1016/S0040-4039(00)80265-8

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