Journal of Medicinal Chemistry p. 1710 - 1721 (1992)
Update date:2022-08-02
Topics: Design and Synthesis Experimental Renin inhibitors 1,2,3-Trisubstituted Cyclopropanes
Martin, Stephen F.
Austin, Richard E.
Oalmann, Christopher J.
Baker, William R.
Condon, Stephen L.
et al.
The 1,2,3-trisubstituted cyclopropanes 6 and 7 are the first members of a novel class of isosteric replacements for peptide linkages that are more generally represented by the dipeptide mimics 2 and 3.These unique peptide surrogates are specifically desig
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