Tetrahedron Letters p. 1419 - 1422 (1991)
Update date:2022-08-02
Topics: Asymmetric synthesis Enantiomer NMR spectroscopy Organocatalysis Chiral Auxiliary Chiral Ligand 1,3-Dipolar Cycloaddition Diastereoselective synthesis Girolline
Commercon
Gueremy
Girolline (RP 49532, 1), a new antitumour agent, was prepared in the racemic series using an oxidation-reduction sequence starting from (±)-erythro-β-chloro-γ-hydroxy- 1-triphenylmethyl-1H-4-imidazolepropanamine 3. The heterocyclic amino function was intr
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Doi:10.1271/bbb1961.39.555
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(2011)
