The choice of chiral ligand is crucial for achieving enantioselectivity in the reaction. Common ligands used in Sharpless AD include (DHQ)2PHAL, (DHQD)2PHAL, and others. The ligand coordinates with the osmium tetroxide, forming a chiral complex.
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(5S)-(5-TERT-BUTYLDIMETHYLSILOXYMETHYL)FURAN-2(5H)-ONE
(1S,2R)-(E)-2-methyl-1-phenyl-3-decen-1-ol
Trichlorosilane
Triethylamine
tert-butyl(2-(chloromethyl)-5-methoxyphenoxy)dimethylsilane
1-(2,4-difluorophenyl)-3-phenylhex-5-en-1-one
Isoquinoline, 1,2,3,4-tetrahydro-1-(phenylmethyl)-, (R)-
(R)-1-(methoxymethyl)-3-(2-(naphthalen-1-yl)-2-oxo-1-phenylethyl)quinolin-2(1H)-one
(6Z)-8-hydroxy-6-[hydroxy(2-methylphenyl)methylene]-2,3-dimethyl-6,7-dihydroindeno[5,6-d]imidazol-5(3H)-one
(Z)-methyl 3-(tert-butoxycarbonylamino)-2-methylacrylate
(4S,5S)-4-cyano-5-<(tert-butyldiphenylsilyl)oxy>methyl-2,2-dimethyl-1,3-dioxolane
1-(2-thienyl)-N-tosylethanimine
Quinoline, 1,2-dihydro-2,2,4-trimethyl-7-(phenylmethoxy)-
2-(((1S,2R)-1-hydroxy-1-phenylpropan-2-ylamino)methyl)-4-nitrophenol
Giracodazole
(R)-(E)-8a-<4-<<(1,1-dimethylethyl)diphenylsilyl>oxy>-3-methyl-2-butenyl>hexahydro-2H-pyrrolo<1,2-a>-pyrazine-1,4-dione
ethyl 2-oxo-4-(4-bromophenyl)-3-buten-1-oate
5-Cyclohexene-1,2,3,4-tetrol, 5-bromo-, (1R,2R,3S,4S)-
C19H25NO5S
(R)-(4-Chlorophenyl)(pyridin-2-yl)methanol
(R)-4,4,5,5-tetramethyl-2-(1-phenylpropyl)-1,3,2-dioxaborolane
((1S,2R,3S,4R)-1-Benzyl-4-tert-butoxycarbonylamino-2,3-dihydroxy-5-phenyl-pentyl)-carbamic acid tert-butyl ester
(+)-(S)-allyl-p-toluenesulphinamide
Butanoic acid, 2-[(benzoylamino)methyl]-3-hydroxy-, methyl ester, (2R,3S)-
