Design and synthesis of novel arylpiperazine derivatives containing the imidazole core targeting 5-HT2A receptor and 5-HT transporter

DOI: 10.1021/jm200682b

Source and publish data:

Journal of Medicinal Chemistry p. 6305 - 6318 (2011)

Update date:2022-09-26

Topics:

Authors:

Seo, Hee Jeong

Park, Eun-Jung

Kim, Min Ju

Kang, Suk Youn

Lee, Suk Ho

Kim, Hyun Jung

Lee, Ki Nam

Jung, Myung Eun

Lee, Minwoo

Kim, Mi-Soon

Son, Eun-Jung

Park, Woo-Kyu

Kim, Jeongmin

Lee, Jinhwa

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Article abstract of DOI:10.1021/jm200682b

Serotonin antagonist reuptake inhibitor (SARI) drugs that block both 5-HT₂ receptors and the serotonin transporters have been developed. The human 5-HT_2A/2C receptor has been implicated in several neurological conditions, and potent

Full text of DOI:10.1021/jm200682b

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