Asymmetric synthesis of 1-hydroxyindolizidines, biosynthetic precursors to the toxic indolizidine alkaloids slaframine and swainsonine

DOI: 10.1016/S0957-4166(00)80439-5

Source and publish data:

Tetrahedron Asymmetry p. 763 - 764 (1990)

Update date:2022-09-26

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Authors:

Takahata

Banba Banba

Momose Momose

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Article abstract of DOI:10.1016/S0957-4166(00)80439-5

An enantioselective synthesis of 1-hydroxyindolizidines (1 and 2) from racemic N-benzyloxycarbonyl-3-hydroxy-4-pentenylamine (3) by following the Sharpless kinetic resolution, intramolecular amidomercuration, and radical Michael addition as key steps is d

Full text of DOI:10.1016/S0957-4166(00)80439-5

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