Chemistry of Heterocyclic Compounds p. 342 - 354 (2011)
Update date:2022-08-04
Topics:
Potikha
Gutsul
Plaskon
Kovtunenko
Tolmachev
The reaction of 3-NHR-isoquinolin-1(2H)-ones (R∈=∈Ar) with aromatic aldehydes in the presence of Me3SiCl or in acetic acid leads to the formation of derivatives of dibenzo[b,f][1, 8]naphthyridin-5(6H)- one and benzo[f]isoquino[3,4-b][1, 8]naphthyridine-5,9(6H,7H)-dione. The reaction for R∈=∈Het in the presence of Me3SiCl gives derivatives of 5H-pyrido[1′,2′:1,2]pyrimido[4,5-c]isoquinolin-5-one, benzo[f]isoquinoline[3,4-b][1,8]naphthyridine-5,9[6H,7H]-dione, and derivatives of new heterocyclic systems, 5H-pyrazino[1′,2′:1,2]pyrimido[4,5-c] isoquinolin-5-one, 5H-[1,3]thiazolo[3′,2′:1,2]pyrimido- [4,5-c]isoquinolin-5-one, 5-H-benzo[f]pyrazolo[3,4-b][1,8]naphthyridin-5-one, and isoquino[3,4-b]- [1,5]naphthyridin-5(6H)-one. The effect of the structure of substituent R and nature of the substituent in the benzaldehydes on the structure of the reaction products was studied.
View MoreNingbo Tide Imp. & Exp. Co., Ltd.
Contact:+86-571-8993 7933; +86-571-8993 6453
Address:7/F Anno Domini Building, Tower South, 8 Qiu Shi Road,Hangzhou,China.
xi'an taima biological engineering co., ltd.
Contact:+8615619038117
Address:6 No,keji road xi'an city of china
Huangshan Violet Biological Technology Co., Ltd
Contact:+86-559-2335676
Address:16-201 JinShanYuan,JiangNan New City,TunXi District,HuangShan City,AnHui Province,China
Beijing Wisdom Chemicals Co., Ltd.
Contact:+86-10-52350335
Address:F2, BLDG 19, Liando Valley U, Majuqiao, Tongzhou District, Beijing, China
Shandong Xinke Petrochemical Co., Ltd.
Contact:+86-546-7277016
Address:Gudao Industrial Park, Hekou District, Dongying, Shandong Province, China
Doi:10.1002/anie.201912584
(2020)Doi:10.1021/ja045521r
(2005)Doi:10.1080/15257779408010666
(1994)Doi:10.1016/j.bmcl.2014.04.061
(2014)Doi:10.1016/j.bmc.2014.04.027
(2014)Doi:10.1007/s10593-014-1489-0
()