Chemistry of Heterocyclic Compounds p. 342 - 354 (2011)
Update date:2022-08-04
Topics:
Potikha
Gutsul
Plaskon
Kovtunenko
Tolmachev
The reaction of 3-NHR-isoquinolin-1(2H)-ones (R∈=∈Ar) with aromatic aldehydes in the presence of Me3SiCl or in acetic acid leads to the formation of derivatives of dibenzo[b,f][1, 8]naphthyridin-5(6H)- one and benzo[f]isoquino[3,4-b][1, 8]naphthyridine-5,9(6H,7H)-dione. The reaction for R∈=∈Het in the presence of Me3SiCl gives derivatives of 5H-pyrido[1′,2′:1,2]pyrimido[4,5-c]isoquinolin-5-one, benzo[f]isoquinoline[3,4-b][1,8]naphthyridine-5,9[6H,7H]-dione, and derivatives of new heterocyclic systems, 5H-pyrazino[1′,2′:1,2]pyrimido[4,5-c] isoquinolin-5-one, 5H-[1,3]thiazolo[3′,2′:1,2]pyrimido- [4,5-c]isoquinolin-5-one, 5-H-benzo[f]pyrazolo[3,4-b][1,8]naphthyridin-5-one, and isoquino[3,4-b]- [1,5]naphthyridin-5(6H)-one. The effect of the structure of substituent R and nature of the substituent in the benzaldehydes on the structure of the reaction products was studied.
View MoreChiral Quest (Suzhou) Company Ltd
website:http://www.chiralquest.com
Contact:+86-0512-62956066
Address:B1/9, 218 Xinghu Street, Suzhou Industrial Park
QINGDAO HONG JIN CHEMICAL CO.,LTD.
website:http://www.hongjinchem.com
Contact:+86-532-83657313
Address:2ND Building, 8 Shangqing Road, Qingdao, Shandong Province, China.
website:http://www.antimex.com
Contact:0086-21-50563169
Address:Room1027,No.Jinyu Road,Pudong
Beijing Green Guardee Technology CO,.LTD
Contact:+86-10-69706062
Address:F2 BLdj,5 No.37 Chaoqian Road
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.
website:http://www.shydtec.com
Contact:86-21-57721279
Address:Science and Technology Park, Songjiang District, Shanghai, China
Doi:10.1002/anie.201912584
(2020)Doi:10.1021/ja045521r
(2005)Doi:10.1080/15257779408010666
(1994)Doi:10.1016/j.bmcl.2014.04.061
(2014)Doi:10.1016/j.bmc.2014.04.027
(2014)Doi:10.1007/s10593-014-1489-0
()