An efficient and practical synthesis of dibenzo[d,f][1,3]-dioxepines from 2,2'-dihydroxybiphenyl with terminal alkynes catalyzed by lewis acid TiCl 4

Article abstract of DOI:10.1002/cjoc.201190225

A synthetic strategy toward the cyclic addition of 2,2'-dihydroxybiphenyl to terminal alkynes has been developed using Lewis acid TiCl₄ as catalyst. The reactions generated dibenzo[d,f][1,3]dioxepines derivatives in good yields with excellent r