Efficient Mannich reaction using iminium salts generated from glycine derivatives

DOI: 10.1246/cl.2011.351

Source and publish data:

Chemistry Letters p. 351 - 353 (2011)

Update date:2022-08-05

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Authors:

Shimizu, Makoto

Kusunoki, Toshiki

Yoshida, Mari

Kondo, Koichi

Mizota, Isao

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Article abstract of DOI:10.1246/cl.2011.351

Iminium salts generated by the oxidation of amino ketene silyl acetals underwent a facile Mannich reaction with another ketene silyl acetal to give aspartic acid derivatives in good yields. The diastereoselectivities were controlled to some extent by usin

Full text of DOI:10.1246/cl.2011.351

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