5-Aryl-1,3,4-oxadiazol-2(3H)-one derivatives and sulfur analogues as new selective and competitive monoamine oxidase type B inhibitors

DOI: 10.1016/0223-5234(90)90131-L

Source and publish data:

European Journal of Medicinal Chemistry p. 659 - 671 (1990)

Update date:2022-08-04

Topics:

Authors:

Mazouz, F.

Lebreton, L.

Milcent, R.

Burstein, C.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0223-5234(90)90131-L

Eighteen new 5-aryl-1,3,4-oxadiazol-2(3H)-one derivatives and sulfur analogues were prepared and evaluated in vitro for their inhibitory properties on monoamine oxidase (MAO) types A and B.The most active compounds in these series acted preferentially aga

Full text of DOI:10.1016/0223-5234(90)90131-L

Products guided by the article

Product name:5-Chloro-2-methoxy-benzoic acid N',N'-bis-(2-cyano-ethyl)-hydrazide

Cas No:133344-95-3

R&D Labs maybe for 133344-95-3

Changsha Botaniex Inc.

Contact:(86) 731 88718666

Address:Room 1222, Unit 4, Building B, Shangcheng, No.47, Kaiyuan East Road.
Tradlon Chemical Co., Ltd.

Contact:+86-710-3516804

Address:Number 83,Panggong road,Xiangcheng District,Xiangyang ,Hubei
JIANGSU GRAND XINYI PHARMACEUTICAL CO.,LTD

website:http://www.xypharm.com/

Contact:+86-515-84383317

Address:Chenli Road,Costal Chemical Area Binhai,Yancheng, Jiangsu,China
Anhui Dexinjia Biopharm Co., Ltd

Contact:+86-531-82375818

Address:9 Hexie Road, kaifaqu, Taihe
Tianjin Crest Pharmaceutical R&D Co., Ltd. （Tianjin Yao Technology Development Co., Ltd.）(expird)

Contact:+86-22-66211386

Address:Building B5-405, No, 80 4th Avenue, TEDA, Tianjin, China P.R. 300457

Relevant to this article

Enantiomerically pure, crystalline 'anti'-aldols from N-acylbornanesultams: Aldolization and structure of intermediate t-butyldimethylsilyl-N,O-ketene acetal

Doi:10.1016/S0040-4039(00)71218-4
(1991)
Covalent assistance in supramolecular synthesis: In situ modification and masking of the hydrogen bonding functionality of the supramolecular reagent isoniazid in co-crystals

Doi:10.1039/c1ce05152k
(2011)
Copper-catalyzed domino one-pot synthesis of 2-(arylselanyl)arylcyanamides

Doi:10.1002/ejoc.201100785
(2011)
Doi:10.1021/jo01285a006
(1967)
Chiral phosphoric acid catalyzed enantioselective transfer hydrogenation of ortho-hydroxybenzophenone N-H ketimines and applications

Doi:10.1002/chem.201101694
(2011)
N-Heterocyclic Carbene Catalyzed 1,6-Conjugate Addition of Me₃Si-CN to para-Quinone Methides and Fuchsones: Access to α-Arylated Nitriles

Doi:10.1021/acs.orglett.7b00508
(2017)

Article Doi