5-Aryl-1,3,4-oxadiazol-2(3H)-one derivatives and sulfur analogues as new selective and competitive monoamine oxidase type B inhibitors

DOI: 10.1016/0223-5234(90)90131-L

Source and publish data:

European Journal of Medicinal Chemistry p. 659 - 671 (1990)

Update date:2022-08-04

Topics:

Authors:

Mazouz, F.

Lebreton, L.

Milcent, R.

Burstein, C.

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Article abstract of DOI:10.1016/0223-5234(90)90131-L

Eighteen new 5-aryl-1,3,4-oxadiazol-2(3H)-one derivatives and sulfur analogues were prepared and evaluated in vitro for their inhibitory properties on monoamine oxidase (MAO) types A and B.The most active compounds in these series acted preferentially aga

Full text of DOI:10.1016/0223-5234(90)90131-L

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