A convenient method for removal of the t-butyl group from nucleoside bis(t-butyl) phosphates under non-acidic conditions

DOI: 10.1016/S0040-4039(00)92637-6

Source and publish data:

Tetrahedron Letters p. 395 - 398 (1991)

Update date:2022-09-26

Topics:

Authors:

Sekine, Mitsuo

Iimura, Shin

Nakanishi, Takeshi

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Article abstract of DOI:10.1016/S0040-4039(00)92637-6

A new method for selective removal of the t-butyl group from 3′ - bis(t-butyl) phosphate esters of 5′-0-(4,4′-dimethoxytrityl)deoxyribo-nucleosides was developed by use of Me₃SiCl and Et₃N. Several unexpected properties of the t-buty

Full text of DOI:10.1016/S0040-4039(00)92637-6

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