C-H arylation of pyridines: High regioselectivity as a consequence of the electronic character of C-H bonds and heteroarene ring

Article abstract of DOI:10.1021/ja206022p

We report a new catalytic protocol for highly selective C-H arylation of pyridines containing common and synthetically versatile electron-withdrawing substituents (NO₂, CN, F and Cl). The new protocol expands the scope of catalytic azine functi