Lipopeptides containing 2-(palmitoylamino)-6,7-bis(palmitoyloxy)heptanoic acid: Synthesis, stereospecific stimulation of B-lymphocytes and macrophages, and adjuvanticity in vivo and in vitro

DOI: 10.1021/jm00111a008

Source and publish data:

Journal of Medicinal Chemistry p. 1969 - 1974 (1991)

Update date:2022-08-05

Topics:

Authors:

Metzger Metzger

Jung Jung

Bessler Bessler

Hoffmann

Strecker

Lieberknecht

Schmidt Schmidt

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Article abstract of DOI:10.1021/jm00111a008

Lipopeptides, carrying the N-terminal lipoamino acid 2-(palmitoylamino)-6,7-bis(palmitoyloxy)heptanoic acid (Pam₃Adh-OH,1), were obtained by solid-phase synthesis and by synthesis in solution. 2-Amino-6,7-dihydroxyheptanoic acid (Adh) can be re

Full text of DOI:10.1021/jm00111a008

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